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1.
Arq. bras. med. vet. zootec. (Online) ; 72(6): 2259-2265, Nov.-Dec. 2020. ilus
Article in Portuguese | LILACS, VETINDEX | ID: biblio-1142302

ABSTRACT

A osteomielite é um desafio terapêutico em ortopedia, capaz de retardar ou mesmo impedir a consolidação óssea. O omento, há anos, tem sido empregado como alternativa em diferentes procedimentos cirúrgicos, por sua capacidade, entre outras, de angiogênese, sendo aplicado na ortopedia veterinária quando há o risco de não união óssea. Neste caso, um cão Fila Brasileiro foi submetido à realização de enxerto com retalho pediculado de omento maior, após osteomielite resistente presente em osteossíntese de fratura múltipla de tíbia aberta grau II. Durante 16 dias, manteve-se a comunicação do retalho, mas, diante do risco de peritonite, o pedículo foi seccionado. Numa sequência de intervenções cirúrgicas, após 89 dias, houve cicatrização óssea e remissão da osteomielite, mesmo na presença de bactérias multirresistentes. Neste relato, o omento foi efetivo como terapia adjuvante no tratamento da osteomielite e garantiu o retorno da função do membro.(AU)


Osteomyelitis is a therapeutic challenge in orthopedics, capable of delaying or even preventing bone healing. The omentum has been used in different surgical procedures as an alternative for its capacity, among others, of angiogenesis, being applied in veterinary orthopedics, when there is a risk of non-union of bone. In this case, a Brazilian row dog was submitted to grafting with pedicle flap of greater omentum, after resistant osteomyelitis present in open fracture osteosynthesis of open tibia grade II. For 16 days the communication of the flap was maintained, but at the risk of peritonitis, the pedicle was sectioned. In a sequence of surgical interventions, after 89 days, there was bone healing and remission of osteomyelitis, even in the presence of multi-resistant bacteria. In this report, the omentum was effective as adjuvant therapy in the treatment of osteomyelitis and guaranteed the return of limb function.(AU)


Subject(s)
Animals , Dogs , Omentum/transplantation , Osteomyelitis/therapy , Osteomyelitis/veterinary , Tibia/pathology , Pedicle Screws/veterinary
2.
Arq. bras. med. vet. zootec. (Online) ; 72(1): 87-92, Jan.-Feb. 2020. ilus
Article in English | LILACS, VETINDEX | ID: biblio-1088928

ABSTRACT

Chronic septic bone nonunion requires a well-designed therapeutic planning, demanding a multimodal treatment to achieve bone consolidation and elimination of infection. A successful case of an association of the major omentum flap with surgical stabilization with an interlocking nail for treatment of a femoral septic nonunion in dog is reported. The patient had partial functional return of the limb 30 days after surgery, negative bacterial culture with radiographic signs of bone healing and total functional return of the limb at 90th days after the surgical procedure.(AU)


Não uniões ósseas associadas à osteomielite crônica necessitam de um planejamento terapêutico muito bem realizado, demandando tratamento multimodal para conseguir atingir a consolidação óssea e eliminar a infecção. Relatou-se um caso de sucesso do uso da associação de retalho do omento maior com estabilização cirúrgica com haste intramedular bloqueada para tratamento de uma não união séptica de fêmur em cão. O paciente apresentou retorno funcional parcial do membro com 30 dias após a cirurgia, cultura bacteriana estéril com sinais radiográficos de consolidação óssea e retorno funcional total do membro aos 90 dias de pós-operatório.(AU)


Subject(s)
Animals , Dogs , Omentum/transplantation , Osteomyelitis/veterinary , Transplantation, Autologous/veterinary , Fracture Fixation, Intramedullary
4.
Acta méd. peru ; 30(4): 135-140, oct.-dic. 2013. ilus, graf, mapas, tab
Article in Spanish | LILACS, LIPECS | ID: lil-702440

ABSTRACT

Introducción: Desde 1990, hemos postulado que la causa primaria de la enfermedad de Parkinson (EP) es de origen isquémico iniciado en el tegmento mesencefálico. Sin embargo, hasta la fecha, casi todos los investigadores consideran que la etiología es desconocida. Objetivo: Demostrar que la EP puede ser mejorada por medio de un transplante de epiplón. Material y Método: Presentamos 3 pacientes con EP avanzado. A través de una craneotomía temporal localizamos la bifurcación carotídea y el espacio perforado anterior (EPA). Aquí encontramos:1) aterosclerosis en las carótidas supraclinoideas, 2) ausencia de la arteria coroidea anterior o de la comunicante posterior, 3) varias arterias perforantes anteriores y posteriores exsangües y 4) aterosclerosis en la bifurcación basilar. El epiplón fue colocado sobre el EPA y fosa interpeduncular. Resultados: La mejoría neurológica fue observada después del tercer día y evidente en las primeras semanas del postoperatorio. Actualmente, 10 y 23 meses después de la cirugía, dos pacientes requieren medicación antiparkinsoniana a dosis reducidas y además, reciben aspirina y clonazepan. Todos los pacientes realizan actividades cotidianas sin asistencia familiar. Conclusiones: Nuestros resultados indican que la EP es causada por isquemia progresiva en el territorio de las arterias perforantes posteriores; porque, en contraste a esto, su revascularización por medio del omento produjo mejoría neurológica. Así mismo, creemos que el uso regular de aspirina y clonazepan puede ayudar a esta enfermedad.


Introduction: Since 1990, we have postulated that the primary cause of Parkinson´s disease (PD) is of ischemic origin initiated in the mesencephalic tegmentum. However, up to date, almost all researchers consider that the etiology is unknown. Objetive.To demonstrates that PD can be improved by means of omental transplantation. Material and Method: We present 3 patients with advanced PD. Through a temporal craniotomy we located the carotid bifurcation and anterior perforated space (APS). Here we found: 1) atherosclerosis at the supraclinoid carotids; 2) absence of anterior choroidal or posterior communicating arteries; 3) several exsanguine anterior and posterior perforating arteries,and 4) atherosclerosis at the basilar bifurcation. The omentum was placed on the APS and interpeduncular fossa. Results: Neurological improvement was observed after the third day and evident in the first weeks postoperatively. At present, 10 and 23 months after surgery, two patients require incomplete antiparkinsonian medication and besides, they receive aspirin and clonazepan. All of them carry out daily activity without assistance familiar. Conclusions: Our results indicate that PD is caused by progressive ischemia in the intraparenchymal territory of the posterior perforating arteries; because, in contrast to this, its revascularization by means of omentum produced neurological improvement .Likewise we believe that the regular use of aspirin and clonazepan may help to this disease.


Subject(s)
Humans , Male , Female , Middle Aged , Aspirin/therapeutic use , Parkinson Disease , Omentum/surgery , Omentum/transplantation
5.
Acta méd. peru ; 30(2): 79-85, abr.-jun. 2013. ilus, graf, mapas, tab
Article in Spanish | LILACS, LIPECS | ID: lil-692315

ABSTRACT

Introducción: En agosto del 2009 operamos el primer paciente con esclerosis lateral amiotrófica (ELA). Sin embargo, hasta la fecha, todo los investigadores informan que no hay cura para esta enfermedad. Objetivo: Demostrar que la ELA puede ser detenida y mejorada mediante un transplante de epiplón. Material y Método: Presentamos a 13 pacientes con formas bulbar y espinal de ELA. Durante la cirugía encontramos: 1) variantes anatómicas del segmento V4 de las arterias vertebrales, 2) aterosclerosis moderada o severa en ambos segmentos V4, 3) algunas arterias circunflejas originadas desde las arterias espinales anteroventrales (AEAVs) exsangües, 4) hipotrofia de raicillas nerviosas en la hilera de los nervios IX, X y XI, 5) en algunos casos, hipotrofia de la superficie anterior de las pirámides e 6) hipotrofia de raíces anteriores en C5 - C6.Todos ellos recibieron transplante de epiplón a la superficie anterior, lateral y posterior de la medula oblongada y en 5 pacientes, un transplante adicional a nivel C5-C6. Resultados: La mejoría neurológica fue observada desde el primer día de la operación y fue mayor durante los primeros días o semanas de la cirugía que en los siguientes meses. Actualmente, 2 pacientes con 8 y 12 meses de evolución postoperatoria han mejorado en un 90% los síntomas de la forma bulbar de ELA. Conclusión: Estos resultados indican que la forma bulbar de ELA es originada por isquemia progresiva en el territorio intraparenquimatoso de las AEAVs y la forma espinal por isquemia en la arteria espinal anterior, pero a nivel C5 a T1. Eso explicaría porque su revascularización por medio del epiplón produjo mejoría neurológica.


Introduction: In August 2009 we performed surgery for the first time in a patient with amyotrophic lateral sclerosis (ALE). However, every published report about ALE mentions there is no cure for this condition. Objective: To prove that the progression of ALE may be stopped and the condition may be improved using an epiplon transplant. Material and Method: This report presents our experience with 13 ALE patients, affected by the bulbar and spinal forms of the disease. During the surgical procedures, we made the following findings: 1) anatomical variants in the V4 segment of vertebral arteries, 2) moderate or severe atherosclerosis in both V4 segments, 3) some circumflex blood vessels originating from the low-flow anterior and ventral spinal arteries, 4) hypothrophy of small nerve roots in the pathway of IX, X, and XI cranial nerves, 5) in some cases, hypothrophy of the anterior surface of the pyramids, and 6) hypothrophy of the anterior roots in C5 - C6. Every patient underwent an epiplon transplant upon the anterior, lateral, and posterior aspects of the medulla oblongata, and 5 patients underwent an additional transplant performed upon the C5-C6 territory. Results: Neurological improvement was seen from the first postoperative day, and it reached its maximum level during the first few days or weeks after surgery. Nowadays, 2 patients after eight and twelve months after surgery have had a 90% symptomatic improvement of the bulbar form of ALE. Conclusion: These results indicate that the bulbar form of ALE is caused by progressive ischemia in the parenchymal territory irrigated by the anterior and ventral spinal arteries, and that the spinal form is caused by ischemia in the anterior spinal artery, affecting the area between C5 and T1. This may explain why this revascularization procedure using epiplon tissue led to neurological improvement.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Omentum/transplantation , Amyotrophic Lateral Sclerosis/surgery , Spinal Cord Ischemia , Lateral Medullary Syndrome , Pyramidal Tracts , Prospective Studies
6.
Journal of Veterinary Science ; : 337-343, 2013.
Article in English | WPRIM | ID: wpr-35280

ABSTRACT

The present study was conducted to compare the effects of xenogenic bovine fetal demineralized bone matrix (DBM), commercial DBM, omentum, omentum-calf fetal DBM, cortical autograft and xenogenic cartilage powder on the healing of tibial defects in a dog model to determine the best material for bone healing. Seven male adult mongrel dogs, weighing 26.2 +/- 2.5 kg, were used in this study. Seven holes with a diameter of 4-mm were created and then filled with several biomaterials. Radiographs were taken postoperatively on day 1 and weeks 2, 4, 6, 8. The operated tibias were removed on the 56th postoperative day and histopathologically evaluated. On postoperative days 14, 42 and 56, the lesions of the control group were significantly inferior to those in the other group (p < 0.05). On the 28th postoperative day, the autograft group was significantly superior to the control and omentum groups (p < 0.05). Moreover, calf fetal DBM was significantly superior to the control group. There was no significant difference between the histopathological sections of all groups. Overall, the omentum and omentum-DBM groups were superior to the control group, but inferior to the autograft, commercial-DBM, calf fetal DBM and calf fetal cartilage groups.


Subject(s)
Animals , Cattle , Dogs , Male , Autografts/transplantation , Biocompatible Materials/therapeutic use , Bone Regeneration , Omentum/transplantation , Wound Healing
7.
Acta cir. bras ; 27(10): 694-701, Oct. 2012. ilus, tab
Article in English | LILACS | ID: lil-650558

ABSTRACT

PURPOSE: To investigate the osteoconductive properties and biological performance of Poly L-lactic acid (PLLA) with omentum in bone defects. METHODS: PLLA nanofiber scaffolds were prepared via electrospinning technique. Forty four New Zealand white female rabbits randomly divided into three groups of 18 rabbits each. Created defects in right tibias were filled in group I with omentum, in group II with PLLA nanofiber scaffold and in group III with combination of the omentum and PLLA. The same defects were created in left tibia of all groups but did not receive any treatment (control group). Histological and histomorphometric evaluations were performed at two, four and six weeks after the implantation. RESULTS: Histological changes on all groups along with the time course were scored and statistical analysis showed that the average scores in group III were significantly higher than the other groups. CONCLUSION: Histomorphometric analysis of bone healing was shown to be significantly improved by the combined PLLA with omentum compared with the other groups, suggesting this biomaterial promote the healing of cortical bone, presumably by acting as an osteoconductive scaffold.


OBJETIVO: Investigar as propriedades de osteocondução e desempenho biológico do ácido L láctico-Poly (PLLA) com omento em defeitos ósseos. MÉTODOS: Andaimes PLLA nanofibras foram preparados via eletrofiação técnica. Cinquenta e quatro coelhos fêmeas Nova Zelândia brancos foram distribuídos aleatoriamente em três grupos de 18 coelhos cada. Defeitos criados em tíbias direitas foram preenchidos no grupo I com omento, no grupo II com PLLA nanofibras e no grupo III com a combinação do omento e PLLA. Os mesmos defeitos foram criados na tíbia esquerda de todos os grupos, mas não receberam qualquer tratamento (grupo controle). As avaliações histológicas e histomorfométricas foram realizadas em duas, quatro e seis semanas após a implantação. RESULTADOS: As alterações histológicas em todos os grupos, juntamente com o curso de tempo foram marcados e análise estatística mostrou que as pontuações médias do grupo III foram significativamente mais elevadas do que os outros grupos. CONCLUSÃO: Análise histomorfométrica da cicatrização óssea mostrou-se significativamente melhor com o PLLA combinado com omento em comparação com os outros grupos, sugerindo que este biomaterial promove a cicatrização do osso cortical, provavelmente atuando como osteocondutor.


Subject(s)
Animals , Female , Rabbits , Bone Regeneration/drug effects , Lactic Acid/therapeutic use , Nanofibers/therapeutic use , Omentum/transplantation , Polymers/therapeutic use , Tibia/injuries , Wound Healing/drug effects , Biocompatible Materials/therapeutic use , Materials Testing , Microscopy, Electron, Scanning , Models, Animal , Time Factors , Tissue Scaffolds , Treatment Outcome
8.
Clinics ; 66(2): 307-312, 2011. ilus, graf, tab
Article in English | LILACS | ID: lil-581519

ABSTRACT

OBJECTIVE: The purpose of this study was to describe the probable mechanism of the volume increase of laparoscopically harvested omentum flaps used to treat breast deformities. METHODS: A histological analysis of omentum samples was performed to study the volume increase of laparoscopically harvested omentum flaps. Samples were harvested immediately after the transposition of the omentum from the abdominal cavity to the breast region and during the second surgical procedure for breast symmetrization of eight patients submitted to the transposition of the omentum flap. Changes in the morphometric measurements of the adipocytes (perimeter, diameter, and area), microvascular density (as measured by the CD31 endothelial marker), and immunohistochemical expression of VEGF were documented. RESULTS: The increases in adipocyte size and microvascular density were statistically significant (P < 0.012). The expression levels of VEGF were lower in the second set of samples when compared to the first set, but the differences were not statistically significant (P < 0.093). CONCLUSION: These results demonstrate an increase in cellular volume as measured by adipocyte perimeter, diameter, and area. Moreover, the increase in the number of vessels in the second set of samples suggests that neoangiogenesis was stimulated by the initial increase in VEGF expression levels observed in the first set of samples. The increase in VEGF expression in the flap may have been caused by adipocyte hypertrophy resulting from neoangiogenesis.


Subject(s)
Adolescent , Adult , Female , Humans , Middle Aged , Young Adult , Adipocytes/cytology , Breast Neoplasms/surgery , Breast/growth & development , Omentum/transplantation , Surgical Flaps , Vascular Endothelial Growth Factors/physiology , Body Mass Index , Breast Neoplasms/blood supply , Breast Neoplasms/pathology , Breast/blood supply , Breast/surgery , Cell Enlargement , Laparoscopy , Neovascularization, Physiologic/physiology , Organ Size , Omentum/blood supply , Omentum/cytology , Postoperative Period , Statistics, Nonparametric , Surgical Flaps/blood supply , Surgical Flaps/pathology , Time Factors
9.
Acta méd. peru ; 27(1): 43-44, ene.-mar. 2010.
Article in Spanish | LILACS, LIPECS | ID: lil-565496

ABSTRACT

Caso clínico: Una mujer de 26 años de edad, presentó una historia de 6 meses de pérdida motora y sensitiva en su pie y pierna derecha causada por cirugía de reemplazo de cadera. Dos estudios electrodiagnósticos revelaron ausencia de neuroconducción en los nervios tibial, peroneal y ciático mayor. Seis meses después, ella recibió un transplante de epiplónen la zona dañada del nervio ciático derecho. Resultados: La mejoría neurológica ocurrió a partir del segundo día de la cirugía. Actualmente a dos años de la cirugía, presenta leve a moderada paresia e hipoestesia en su pie y pierna derecha. Ella camina con ayuda de aparatos ortopédicos. Conclusión: Estos resultados indican que con esta modalidad quirúrgica podemos mejorar las secuelas causadas por isquemia y/o trauma en el nervio ciático mayor, y probablemente, en plexo braquial.


Clinical case: A 26-year old woman had a 6-month history of motor and sensorial loss in her right foot and leg after undergoing a hip replacement surgery. Two electro-diagnostic studies revealed absence of nerveconduction in tibial, fibular, and sciatic nerves. Six moths afterwards, the patient underwent an omental transplantation in the damaged area of the right sciatic nerve. Results: Neurological improvement occurred from the second day after surgery. Nowadays, two years after surgery, the patient has mild to moderate paralysis and hypoesthesia in her right foot and leg. The patient is able to walk using orthopedic support. Conclusion: These results indicate that with this surgical approach we may be able to get over the sequels caused by ischemia and/or trauma in the sciatic nerve; and probably this may also apply to the brachial plexus.


Subject(s)
Humans , Adult , Female , Omentum/transplantation , Sciatic Nerve/injuries
10.
Clinics ; 65(4): 401-406, 2010. ilus, tab
Article in English | LILACS | ID: lil-546315

ABSTRACT

OBJECTIVE: For patients with Poland's syndrome, a transverse skin fold in the anterior axillary pillar, infra-clavicular depression and an anomalous breast contour are the most uncomfortable disfigurements. This study aims to demonstrate that superior aesthetic results can be achieved by using a laparoscopically harvested omentum flap to treat this condition. METHODS: From a prospectively maintained clinical database of patients undergoing a laparoscopic omentum flap procedure for breast reconstruction, all of the patients with Poland's syndrome were identified and their outcomes were studied. RESULTS: Thirteen consecutive patients with Poland's syndrome were treated and evaluated regarding breast contour, reconstruction of the anterior axillary pillar and filling of the infra-clavicular depression. Implants were employed beneath the flap in 76 percent of cases to improve symmetry. In 23 percent of cases, a contra-lateral mastopexy was performed, and in 15 percent of cases, a breast implant was used. The consistency of the flap is similar to natural breast tissue and only a small incision in the breast fold is needed. The majority of patients (85 percent) were female, with a mean age of 26 (18-53). The flap is extremely malleable, adapts to irregular surfaces, and has a long vascular pedicle. Additionally, its removal does not leave a scar at the donor site as the removal of muscular flaps does. For example, the removal of the latissimus dorsi flap causes a deformity in the dorsal contour. The mean operative time was 201 minutes (80-350) and the mean hospital stay was 2.3 days (1-5). CONCLUSIONS: The outcomes of these patients revealed that the omentum flap technique provided superior amelioration of the deformities caused by Poland's syndrome when compared with other reconstructive options.


Subject(s)
Adolescent , Adult , Female , Humans , Male , Middle Aged , Young Adult , Breast/abnormalities , Laparoscopy/methods , Mammaplasty/methods , Omentum/transplantation , Poland Syndrome/surgery , Surgical Flaps , Abdominal Cavity/surgery , Axilla/anatomy & histology , Treatment Outcome , Young Adult
11.
Acta méd. peru ; 26(2): 92-94, abr.-jul. 2009. ilus
Article in Spanish | LILACS, LIPECS | ID: lil-539363

ABSTRACT

Introdución. La neurálgia occipital es una causa común de cefalea, que puede ser primaria o secundaria, y la meta del tratamiento es aliviar el dolor. Caso clínico. Un hombre de 51 años de edad fue admitido con una historia de 6 semanas de neurálgia occipital primaria. El dolor empezó en el área lateral izquierda del cuello y ocasionalmente, en el lado derecho. Tuvo una historia fumador desde los 15 años de edad. A la edad de los 30, 40 y 45 años, respectivamente, sufrió tres episodios de neurálgia occipital con una duración promedio de 4 meses cada una. El examen neurológico fue normal. Una tomografía computada reveló aterosclerosis en el segmento V4 de la arteria vertebral izquierda. Un transplante de epiplón sobre la medula cervical alta y superficie dorsocaudal de la medula oblongada fue realizada. El patiente experimentó alivio completo del dolor desde el primer día de la operación. Conclusión. Actualmente a dos años de la cirugía, la neurálgia occipital primaria a desaparecido. Este resultado sugiere que neuronas isquémicas en la porción caudal de los subnúcleo caudalis del trigémino, son las responsables de la neurálgia occipital primaria.


Introduction. Occipital neuralgia is a common cause of headache, it may be primary or secondary, and the goal of therapy is to alleviate pain. Case report. A 51-year-old man was admitted with a 6-week history of primary occipital neuralgia. Pain began at the left lateral area of the neck and sometimes it took the right side. The patient had been a smoker since he was 15 years old. When he was 30, 40, and 45 years old, he had three episodes of left occipital neuralgia, and their average duration was 4 months in each time. Neurological examination was normal. A CT scan showed atherosclerosis in the V4 segment of the left vertebral artery. An omental transplantation upon the upper cervical cord and the dorsal and caudal surface of the medulla oblongata was performed. The patient experienced complete relief of his pain since the very first day after the procedure. Conclusion. Nowadays, two years after surgery, the patient has no primary occipital neuralgia. This result suggests that ischemic neurons in the caudal portions of subnucleus caudalis are responsible for primary occipital neuralgia.


Subject(s)
Humans , Male , Middle Aged , Vertebral Artery , Intracranial Arteriosclerosis/therapy , Omentum/surgery , Omentum/transplantation , Neuralgia/therapy
12.
Rev. med. nucl. Alasbimn j ; 8(31)jan. 2006. ilus
Article in English | LILACS | ID: lil-444082

ABSTRACT

Se ha comunicado mejoría clínica después del implante quirúrgico de Omento (delantal de los epiplones) en el cerebro en varias condiciones neurológicas que incluyen Infarto cerebral, Encefalitis, Transecciones de la médula espinal y enfermedad de Alzheimer's. La explicación fisiopatológica de estas mejorías no es conocida pero puede relacionarse con la presencia de Células Madres y factores de crecimiento en el Omento que tendrían efectos sobre la angiogénesis, neurogénesis y sobrevida neuronal. El presente trabajo describe los cambios en la actividad cerebral en dos pacientes con diagnóstico de Enfermedad de Alzheimer's confirmado por biopsia, cuya evolución clínica había entrado a una fase de rápida progresión antes del trasplante de Omento. Los pacientes fueron evaluados psicométricamente mediante la escala de clínica de severidad demencial , desde el punto de vista cognitivo el MMSE examination y Neurospect sequencial con HMPAO medido durante 22 y 42 meses respectivamente. La severidad de la demencia mejoró durante dos o más años, mientras la actividad cortical en áreas bajo, adyacente y contralateral al Omento implantado aumentó en una o dos desviaciones standard sobre los niveles pre-operativos del paciente (el máximo aumento fue un 21 por ciento, cuatro desviaciones standard). En el paciente con menor severidad de demencia se observó a los 22 meses post-trasplante que el cingulado posterior demostraba un aumento de perfusión de 20 por ciento comparado con el nivel pre-operativo. Esto es notable si consideramos que el Omento no tenía un contacto directo con la corteza cingulada posterior que se ve envuelta en las fases iniciales de la Enfermedad de Alzheimer's (Braak y Braak etapas 3-4). Estos hallazgos justifican investigación respecto de los mecanismos por los cuales el Omento puede mejorar la actividad cerebral cortical y las funciones clínicas durante dos o más años en la enfermedad de Alzheimer's.


Subject(s)
Humans , Cerebrovascular Circulation/physiology , Alzheimer Disease , Alzheimer Disease/surgery , Omentum/transplantation , Tomography, Emission-Computed, Single-Photon , Cerebrum/physiology , Cerebral Cortex , Cerebral Cortex/blood supply , Recovery of Function/physiology , Cerebral Revascularization
13.
Indian J Cancer ; 2004 Oct-Dec; 41(4): 167-9
Article in English | IMSEAR | ID: sea-49478

ABSTRACT

BACKGROUND: The standard of care of patients with cancer of cardia and esophagus still remains surgery in early stage. One of the most feared complications after such procedure is anastomotic leak. AIM: We present our experience with omental wrapping of anastomosis (omentoplasty) to decrease the anastomotic leak. SETTINGS AND DESIGN: Retrospective study. MATERIALS AND METHODS: An analysis of 50 consecutive patients, who underwent surgical resection for cancer of cardia and esophagus at BPKMCH, is done. For cancer of esophagus, a 10 cm proximal tumor free margin and for lesions of cardia, at least 5 cm margin was achieved. A 5 cm distal tumor free margin was achieved in each case. A subset of patients was considered for omentoplasty after completion of anastomosis. RESULTS: There were 29 male and 21 female with a mean age of 56.3 years. The average postoperative stay was 13.14 days. The stomach was the organ of substitute in 48 and jejunum in 2 cases. Omentoplasty was done in 37 cases, whereas in 13 cases, no omental wrapping was done. The rate of anastomotic leak was 6%. There was no leak from anastomosis placed at chest, whereas three cases of leak was observed in the anastomosis at the level of neck (P=.013). Overall, there was no leak in omentoplasty group, whereas there were three cases with leak in the group without omentoplasty (P=0.003). CONCLUSION: Omentoplasty should be considered in every case after surgical resection for cancer of cardia and esophagus.


Subject(s)
Adult , Aged , Aged, 80 and over , Anastomosis, Surgical/methods , China/epidemiology , Esophageal Neoplasms/surgery , Esophagectomy/methods , Female , Gastrostomy/methods , Humans , Male , Middle Aged , Omentum/transplantation , Postoperative Complications/epidemiology , Retrospective Studies , Stomach Neoplasms/surgery
14.
Neurol India ; 2002 Mar; 50(1): 71-4
Article in English | IMSEAR | ID: sea-121211

ABSTRACT

The authors present two patients, with poorly controlled temporal lobe epilepsy, who received transplants of omental tissue on the anterior perforated space and left temporal lobe. At present, 26 months after the operation, the first patient has improved about 85 percent; whereas the second patient has complete control of seizures nine months after the operation. These clinical results indicate that epileptic seizures can be reduced or aborted with this new surgical modality (reconstructive technique).


Subject(s)
Adult , Epilepsy, Temporal Lobe/diagnostic imaging , Female , Humans , Male , Omentum/transplantation , Tomography, X-Ray Computed , Treatment Outcome
15.
Neurol India ; 2000 Dec; 48(4): 319-21
Article in English | IMSEAR | ID: sea-120935

ABSTRACT

The acetylcholine, dopamine, serotonin and other neurotransmitters may be reduced in the subcommissural regions even in the early stages of Alzheimer's disease(AD), due to hypoperfusion of the anterior perforating and anterior choroidal arteries. This hypothesis was confirmed after the transplant of omental tissue on the optic chiasma, carotid crotch and anterior perforated space in a woman with moderate AD. Neurological improvement was better in the first week after the surgery than in the following months.


Subject(s)
Alzheimer Disease/physiopathology , Cerebrovascular Circulation/physiology , Choroid Plexus/physiology , Circle of Willis/physiology , Female , Humans , Middle Aged , Omentum/transplantation , Optic Chiasm/blood supply , Tomography, X-Ray Computed
16.
Rev. bras. cir. cardiovasc ; 15(1): 23-31, jan.-mar. 2000.
Article in Portuguese | LILACS | ID: lil-255090

ABSTRACT

CASUÍSTICA E MÉTODOS: Foram analisados 22 casos de mediastinite que ocorreram após 1006 operações cardíacas com esternotomia, realizadas de 1993 a 1998, no Hospital Felício Rocho em Belo Horizonte, Minas Gerais. A complicação ocorreu em 3,2 porcento dos coronariopatas, 3,1 porcento dos transplantados, 1,1 porcento dos valvares e não ocorreu em portadores de defeitos congênitos. RESULTADOS: O índice geral de mediastinite foi de 2,1 porcento. O microorganismo mais comumente responsável pela infecção foi o Staphylococcus aureus (39,1 porcento). Diversas modalidades terapêuticas para mediastinite foram utilizadas no período: drenagem simples, desbridamento e granulação, rotação de retalho de músculo peitoral e rotação do grande epíploon. CONCLUSÃO: A rotação do retalho de grande epíploon, introduzida no Serviço em 1995 para tratamento dos casos de mediastinite, proporcionou excelentes resultados, não ocorrendo óbitos pela complicação nos últimos 2,5 anos


Subject(s)
Humans , Male , Female , Middle Aged , Cardiac Surgical Procedures/adverse effects , Mediastinitis/surgery , Omentum/transplantation , Sternum/surgery , Surgical Flaps , Incidence , Mediastinitis/microbiology , Mediastinitis/mortality , Postoperative Complications , Preoperative Care , Reoperation , Staphylococcus aureus/isolation & purification , Survival Rate , Treatment Outcome
18.
Acta cir. bras ; 13(3): 172-6, jul.-set. 1998. tab
Article in Portuguese | LILACS | ID: lil-236110

ABSTRACT

Desde o século XIX o omento maior vem sendo utilizado em diferentes procedimentos cirúrgicos. O objetivo desse estudo foi avaliar os efeitos da omentoplasia na cicatrização de anastomoses colônicas em ratos. Utilizaram-se 64 ratos machos, que foram divididos em 4 grupos (A, AN, B, C). Realizou-se uma anastomose colônica situada há 5cm da borda anal, de três maneiras diferentes: para os grupos A e AN, anastomose padrão com 8 pontos seromusculares; para o grupo B, anastomose isquêmica e, para o grupo C uma anastomose deficiente com apenas 4 pontos. Na metade dos animais de cada grupo a anastomose foi recoberta com o omento e desta forma obteve-se os subgrupos AO, ANO, BO, CO. No grupo AN e ANO utilizou-se tinta nanquim para avaliar a neovascularização. Todos os animais foram submetidos a eutanásia no 7§ dia de pós-operatório. Concluiu-se que a utilização da omentoplastia promoveu, uma neovascularização na área de anastomose, aumentou a presença de colágeno e levou a uma diminuição da presença de ader6encias próximo da linha de sutura.


Subject(s)
Animals , Male , Rats , Colon/surgery , Omentum/transplantation , Surgical Flaps , Wound Healing , Anastomosis, Surgical/methods , Peritoneal Diseases/surgery , Rats, Wistar , Statistics, Nonparametric
19.
Cir. & cir ; 66(4): 155-8, jul.-ago. 1998. ilus
Article in Spanish | LILACS | ID: lil-243046

ABSTRACT

Estudios previos sugieren que es posible revascularizar estructuras subcorticales. Presentamos a una mujer de 66 años de edad con afasia motora, severa disfasia sensorial, hemiplejía espástica, hemi-anestesia y dolor talámico en sus miembros derechos por trombosis de la arteria cerebral media izquierda, quien recibió un trasplante de epiplón sobre el espacio perforado anterior. Después de cirugía presentó hemi-hipoestesia, desaparición del dolor talámico y mejoría de la disfasia sensorial. Estos resultados confirman que es factible mejorar la función de estructura corticales y subcorticales en isquemia y penumbra isquémica por medio del omento


Subject(s)
Humans , Female , Aged , Cerebral Infarction/diagnosis , Cerebral Infarction/surgery , Omentum/anatomy & histology , Omentum/transplantation , Diagnostic Techniques, Surgical , Pain/physiopathology , Thalamus , Tomography, X-Ray Computed
20.
Rev. bras. cir ; 87(3): 97-101, maio-jun. 1997. ilus
Article in Portuguese | LILACS | ID: lil-199570

ABSTRACT

No presente artigo é relatado um caso grave de perda de substância de parede de regiäo torácica anterior em paciente submetido a esternotomia medianapara revascularizaçäo miocárdica. O paciente evoluiu com deiscência da esternotomia, osteomielite de esterno e mediastinite, cujo tratamento local através de amplo debridamento resultou em grande área cruenta. Utilizou-se, para reconstruçäo, retalho de grande omento o qual foi obtido através de técnica videolaparoscópica e tranposto para a regiäo torácica, complementando-se com enxertia de pele. Os autores comentam o procedimento e revisam sumariamente os relatos na literatura mundial até a presente data


Subject(s)
Humans , Male , Middle Aged , Surgical Wound Dehiscence/surgery , Laparoscopy , Omentum/transplantation , Sternum/surgery , Surgical Flaps
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